Holiday - you are really the only person who can decide what's right for you.
I posed a similar question nearly four years ago at Christmas.com when I was faced with a decision I had to make about where I was going to wake up on Christmas morning. My father was struggling with cancer, but we had already made plans to start taking turns and spending more time with our boys and the grandchildren during the Christmas holidays. I have countless wonderful memories and my husband has so few. I wanted to do something special for him and I knew spending time with the children would make his Christmas more special. I struggled with my decision because of a comment my father had made. At the time I thought it was a "guilt trip" thing. I realized after that he was going to have a hard time not having me home on Christmas morning rushing over to help him collect the luminary bags and spending most of the day together and dealing with my mother's tears over it, etc. It's hard to believe I was visiting grandchildren on Christmas morning the first time I celebrated Christmas away from my mom and dad.
It was a little sad off and on, but I am so glad that I did it. My dad thankfully survived his battle with cancer and he just one a golf tournament.
The cabin sounds like a nice place to celebrate Thanksgiving. I'd love to go to a cabin in the woods if I wasn't going to be home. My husband and I are planning something like that next year for our Anniversary which falls around the time of the Canadian Thanksgiving weekend.
I am one of the most traditional people I know and I surprised myself by celebrating in a different way and really enjoyed it.
As for the long car ride, toss some Christmas tunes on and enjoy the ride.
But . . .
It sounds to me like you want to stay home, but you are not sure how to tell the rest of the family about your decision. Perhaps reaching one soon, will give them time to invite another couple (if they wish) to join them instead.